As per recent reports, Rockstar Games is eyeing Seattle as the next map runner and considers Emerald City for the upcoming installment of Rockstar series. While Seattle may not have the "GTA 6" level of violence and crime, it is possible to mend this by introducing small tweaks in the storyline and use the economic and geographical elements offered by the large US city. The news report also highlights that Seattle is an appropriate fit for the smuggling storyline that developer Rockstar Games is planning to bring in to "Grand Theft Auto 6."
Speaking of Seattle, the one thing that comes time mind is "GTA 4," due to the influence of martial arts and final resting place of Bruce Lee, the Hollywood legend. Rockstar used that influence to create an independent "GTA 4" star, Brucie Kibbutz. This character is a fan of steroid-taking Bruce Lee who hung out with Russians in "GTA."
Similarly, Rockstar could develop a similar, or better side character for "GTA 6." For the benefit of the developers, Seattle is also an important point of trade between North America and Asia. By that logic, smuggling ring story has a strong potential if the game adds Seattle map.
However, it is important to note that E3 2016 brought no word on "GTA 6," but the rumor has it that the game will release in 2020, thanks to the continued success of "GTA Online." Eva Mendes and Ryan Gosling reportedly are the protagonists for "GTA 6."