Pope Francis presided over Easter Mass in St. Peter's Square on Sunday despite ongoing health issues that limited his activities at other Holy Week events.
Francis, 87, led an estimated 30,000 people in Easter celebrations in St. Peter's Square.
Easter Mass is one of the most important events of the year for Catholics, celebrating Jesus' resurrection after his crucifixion.
After the service, Francis made several loops around the crowd in his popemobile, greeting well-wishers.
He then delivered a prayer for peace and appealed for a cease-fire in Gaza and a prisoner swap between Russia and Ukraine, according to the Associated Press.
"I appeal once again that access to humanitarian aid be ensured to Gaza, and call once more for the prompt release of the hostages seized on last October 7 and for an immediate cease-fire in the Strip," he said in his Urbi et Orbi address, according to Reuters.
The pope has been dealing with various health issues including respiratory problems.
He opted not to deliver his homily a week ago during Palm Sunday Mass in St. Peter's Square, in an apparent last-minute decision.
Francis also skipped the annual Good Friday procession at the last minute.
In a brief statement, the Vatican said the decision was made to conserve the Pope's health so close to the vigil service on Saturday and the taxing obligations of Easter Sunday.